Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29240842 | 0.79 | KDM4E (0.48) | KDM4EMAPTTDP1TSHRADORA3 | |
| SCHEMBL28091052 | 0.71 | KDM4E (0.48) | KDM4EMAPTTSHRADORA3MC4R | |
| SCHEMBL10805701 | 0.68 | ADORA3 (0.47) | KDM4EMAPTTDP1TSHRADORA3 | |
| SCHEMBL21722722 | 0.65 | POLB (0.67) | KDM4EMAPTTDP1TSHRADORA3 | |
| SCHEMBL27615063 | 0.65 | KMT2A (0.68) | KDM4EMAPTTDP1TSHRPOLB | |
| SCHEMBL11202262 | 0.65 | SMN1; SMN2 (0.59) | KDM4EMAPTTDP1POLBKMT2A | |
| SCHEMBL18768805 | 0.65 | — | — | |
| Pyrazinamide SCHEMBL18364991 | 0.65 | — | — | |
| Pyrazinamide SCHEMBL18364989 | 0.65 | — | — | |
| Pyrazinamide SCHEMBL24102 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886801-A | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4886801-A | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4788198-A | ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0137979-B1 | DIAZINE-ETHENYLPHENYL OXAMIC ACIDS AND ESTERS AND SALTS THEREOF | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1988-10-26 | — | — | EP | disclosed |
| US-4681884-A | ANTIALLERGEN, ANTIINFLAMMATORY | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4681884-A | ANTIALLERGEN, ANTIINFLAMMATORY | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0137979-A1 | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0137979-A1 | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1985-04-24 | — | — | EP | disclosed |