SCHEMBL10496100

SCHEMBL10496100

COC(=O)C(F)(F)C(F)(F)S(C)(=O)=O

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.32
PRSS1 P07477 3/20 0.32
PRSS2 P07478 3/20 0.32
PRSS3 P35030 3/20 0.32
ALDH1A1 P00352 1/20 0.32
DGAT1 O75907 1/20 0.32
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25713874 0.87 F2 (0.33) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL10888075 0.84
SCHEMBL11927759 0.82 F2 (0.32) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL517250 0.77 ALDH1A1 (0.45) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL15491315 0.76 DGAT1 (0.34) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL10888078 0.75
SCHEMBL10496124 0.73 ALDH1A1 (0.40) ALDH1A1L3MBTL1
SCHEMBL497763 0.72 DGAT1 (0.39) ALDH1A1DGAT1GAA
SCHEMBL1129794 0.72 ALDH1A1 (0.42) ALDH1A1DGAT1GAAL3MBTL1
SCHEMBL517272 0.72 DGAT1 (0.39) ALDH1A1DGAT1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4851161-A β-substituted polyfluoropropionate salts and derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-25 US disclosed
EP-0062430-B1 PROCESS FOR THE PREPARATION OF (OMEGA-FLUOROSULFONYL) HALOALIPHATIC CARBOXYLIC ACID FLUORIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-11-12 EP disclosed
US-4474700-A β-Substituted polyfluoropropionate salts and derivatives E. I. Du Pont DeNemours and Company (US) 1984-10-02 US disclosed
US-4466881-A ELECROLYTIC FLUORINATION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-08-21 US disclosed
US-4425199-A FLUORINATION, ELECTROLYSIS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-01-10 US disclosed
EP-0070635-A2 Beta-substituted polyfluoropropionate salts and derivatives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-26 EP disclosed
EP-0062430-A1 Process for the preparation of (omega-fluorosulfonyl) haloaliphatic carboxylic acid fluorides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-10-13 EP disclosed