SCHEMBL497763

SCHEMBL497763

COC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.39
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.36
KCNN4 O15554 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
SRC P12931 1/20 0.31
GAA P10253 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
TSHR P16473 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
CTRB1 P17538 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082673 0.97 THRB (0.40) DGAT1ALDH1A1THRBKCNN4HDAC1
SCHEMBL11205420 0.97 THRB (0.40) DGAT1ALDH1A1THRBKCNN4HDAC1
SCHEMBL517251 0.97 THRB (0.40) DGAT1ALDH1A1THRBKCNN4HDAC1
SCHEMBL672362 0.97 THRB (0.40) DGAT1ALDH1A1THRBKCNN4HDAC1
SCHEMBL517272 0.94 DGAT1 (0.39) DGAT1ALDH1A1THRBKCNN4SRC
SCHEMBL2690305 0.92 THRB (0.48) DGAT1ALDH1A1THRBKCNN4HDAC1
SCHEMBL196434 0.90 THRB (0.52) DGAT1ALDH1A1THRBHDAC1HDAC7
SCHEMBL198030 0.90 THRB (0.52) DGAT1ALDH1A1THRBHDAC1HDAC7
SCHEMBL10767125 0.90 DGAT1 (0.33) DGAT1ALDH1A1THRBKCNN4HDAC1
SCHEMBL497426 0.90 THRB (0.52) DGAT1ALDH1A1THRBHDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120119471-A Preparation method of cotton-based oil-water separation material based on enzyme catalytic polymerization 绍兴文理学院 2025-06-10 CN claimed
EP-3446177-B1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORP (US) 2024-02-28 EP claimed
CN-117187312-A Method for synthesizing fluorine-containing polyester by esterase catalysis 深州市工程塑料有限公司 2023-12-08 CN claimed
CN-112300631-A Ink for ink-jet printing, preparation method thereof and light-emitting device 广东聚华印刷显示技术有限公司 2021-02-02 CN claimed
US-10459307-B2 Flame retardancy of electrochromic devices GENTEX CORPORATION (US) 2019-10-29 US claimed
WO-2017183004-A1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2017-10-26 WO claimed
US-20170307952-A1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORPORATION 2017-10-26 US claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20240227364-A9 GLAZING WITH ACTIVE AREAS THE CONTROLS OF WHICH ARE IDENTIFIED BY SIGNS PRODUCED USING DIGITAL PRINTING SAINT-GOBAIN SEKURIT FRANCE (FR) 2024-07-11 US disclosed
US-20240131821-A1 GLAZING WITH ACTIVE AREAS THE CONTROLS OF WHICH ARE IDENTIFIED BY SIGNS PRODUCED USING DIGITAL PRINTING SAINT GOBAIN (FR) 2024-04-25 US disclosed
EP-4353705-A1 ALCOHOL PRODUCTION METHOD AND COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-04-17 EP disclosed
US-20240109826-A1 ALCOHOL PRODUCTION METHOD AND COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-04-04 US disclosed
EP-3446177-B1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORP (US) 2024-02-28 EP disclosed
CN-117295705-A Alcohol production method and composition 大金工业株式会社 2023-12-26 CN disclosed
US-20040072987-A1 3,4-Alkylenedioxythiophene compounds and polymers thereof AGFA-GEVAERT (BE) 2004-04-15 US disclosed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN disclosed
EP-0998521-B1 EXPANDABLE HOLLOW PARTICLES GORE ENTERPRISE HOLDINGS INC (US) 2002-10-30 EP disclosed
EP-0998521-A1 EXPANDABLE HOLLOW PARTICLES Gore Enterprise Holdings, Inc. (US) 2000-05-10 EP disclosed
WO-1999002589-A1 EXPANDABLE HOLLOW PARTICLES GORE ENTERPRISE HOLDINGS, INC. (US) 1999-01-21 WO disclosed
US-5834526-A Expandable hollow particles W. L. GORE & ASSOCIATES, INC. 1998-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109826-A1 ALCOHOL PRODUCTION METHOD AND COMPOSITION ADH1A, ADH1C, ADH5 DGAT1 590/4885ALDH1A1 50/4885THRB 2675/4885
US-20040072987-A1 3,4-Alkylenedioxythiophene compounds and polymers thereof CCNT1, TTI1, SULT1E1 DGAT1 481/4885ALDH1A1 221/4885THRB 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.