Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.58 |
| ▸ | ACHE | P22303 | 9/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.56 |
| ▸ | TUBB | P07437 | 2/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497183 | 1.00 | BCHE (0.58) | BCHEACHECYP1B1TUBB4ATUBB | |
| SCHEMBL10497550 | 0.95 | MAPT (0.56) | BCHEACHECYP1B1TUBB4ATUBB | |
| SCHEMBL10497576 | 0.95 | MAPT (0.56) | BCHEACHECYP1B1TUBB4ATUBB | |
| SCHEMBL10497645 | 0.88 | TUBB4A (0.53) | BCHEACHETUBB4ATUBBTUBA3C | |
| SCHEMBL10497639 | 0.88 | TUBB4A (0.53) | BCHEACHETUBB4ATUBBTUBA3C | |
| SCHEMBL10498623 | 0.87 | MAOB (0.58) | CYP1B1MAOBMAOAMAPTLMNA | |
| SCHEMBL10498629 | 0.87 | MAOB (0.58) | CYP1B1MAOBMAOAMAPTLMNA | |
| SCHEMBL10497601 | 0.87 | MAOB (0.58) | CYP1B1MAOBMAOAMAPTLMNA | |
| SCHEMBL9339789 | 0.87 | ABCG2 (0.53) | BCHEACHECYP1B1MAPTLMNA | |
| SCHEMBL9342016 | 0.87 | MAPT (0.57) | CYP1B1MAOBMAOAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | claimed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |