Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 7/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497576 | 1.00 | MAPT (0.56) | MAPTCYP3A4ALDH1A1HPGDRAB9A | |
| SCHEMBL10497183 | 0.95 | BCHE (0.58) | MAPTCYP3A4KMT2ABCHEACHE | |
| SCHEMBL10497170 | 0.95 | BCHE (0.58) | MAPTCYP3A4KMT2ABCHEACHE | |
| SCHEMBL10497645 | 0.88 | TUBB4A (0.53) | BCHEACHEMAOBABCG2HDAC1 | |
| SCHEMBL10497639 | 0.88 | TUBB4A (0.53) | BCHEACHEMAOBABCG2HDAC1 | |
| SCHEMBL9342016 | 0.87 | MAPT (0.57) | MAPTCYP3A4ALDH1A1HPGDRAB9A | |
| SCHEMBL10498629 | 0.87 | MAOB (0.58) | MAPTALDH1A1RAB9AKMT2AMAOB | |
| SCHEMBL9339786 | 0.87 | ABCG2 (0.53) | MAPTCYP3A4ALDH1A1HPGDRAB9A | |
| SCHEMBL10497601 | 0.87 | MAOB (0.58) | MAPTALDH1A1RAB9AKMT2AMAOB | |
| SCHEMBL10498623 | 0.87 | MAOB (0.58) | MAPTALDH1A1RAB9AKMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | claimed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |