Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 5/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338473 | 0.91 | CYP1A1 (0.37) | THRBCYP1A2MEN1KMT2A | |
| SCHEMBL10498782 | 0.79 | MAOB (0.52) | MEN1KMT2A | |
| SCHEMBL9341646 | 0.78 | CYP1A1 (0.45) | THRBCYP1A2 | |
| SCHEMBL9338349 | 0.78 | DPP4 (0.39) | THRB | |
| SCHEMBL10497544 | 0.78 | THRA (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497387 | 0.76 | CNR2 (0.42) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497285 | 0.76 | THRA (0.41) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497559 | 0.76 | MEN1 (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497748 | 0.76 | THRA (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497813 | 0.76 | ABCG2 (0.48) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |