Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | TFEB | P19484 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497748 | 0.93 | THRA (0.43) | LMNAMAPTCYP1A2RECQLTHRA | |
| SCHEMBL10497826 | 0.91 | THRA (0.43) | LMNACYP1A2CYP3A4RECQLTHRA | |
| SCHEMBL10497997 | 0.90 | NFE2L2 (0.49) | NFE2L2PLK1MAOBNPC1BCHE | |
| SCHEMBL9338443 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9338184 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9338690 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9342044 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9341570 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9341391 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9337765 | 0.88 | LMNA (0.41) | NFE2L2LMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |