Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497175 | 0.83 | KDM4E (0.47) | KMT2AMEN1USP2KDM4ERAB9A | |
| SCHEMBL7194480 | 0.80 | CYP1A2 (0.58) | KMT2AMEN1CYP1A2PDE5ANPC1 | |
| SCHEMBL4847814 | 0.79 | KDM4E (0.53) | KMT2AMEN1TUBB4ATUBBTUBA3C | |
| SCHEMBL10497610 | 0.79 | CYP3A4 (0.53) | KMT2AMEN1CYP1A2TUBB4ATUBB | |
| SCHEMBL2029774 | 0.78 | MEN1 (0.64) | KMT2AMEN1USP2NPC1CASP3 | |
| SCHEMBL10497874 | 0.78 | KMT2A (0.68) | KMT2AMEN1NPSR1KDM4EMAPT | |
| SCHEMBL644055 | 0.77 | KDM4E (0.57) | KMT2AMEN1CYP1A2PDE5ATUBB4A | |
| SCHEMBL987157 | 0.77 | TUBB4A (0.45) | KMT2AMEN1CYP1A2PDE5ATUBB4A | |
| SCHEMBL28329924 | 0.75 | KDM4E (0.64) | KMT2AMEN1TUBB4ATUBBTUBA3C | |
| SCHEMBL6129112 | 0.75 | L3MBTL1 (0.59) | KMT2AMEN1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |