SCHEMBL987157

SCHEMBL987157

COc1cc(OC)c(OC)c(C(=O)Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45
TUBB2B Q9BVA1 1/20 0.45
TUBB1 Q9H4B7 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
CYP3A4 P08684 2/20 0.43
USP2 O75604 1/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10497610 0.83 CYP3A4 (0.53) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL4847814 0.83 KDM4E (0.53) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL11179253 0.81 KDM4E (0.54) CYP3A4MAPTPOLBKDM4E
SCHEMBL644055 0.81 KDM4E (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15233646 0.81 KDM4E (0.51) SMN1; SMN2CYP3A4USP2MAPTHTT
SCHEMBL985501 0.80 FAAH (0.55) SMN1; SMN2HTT
SCHEMBL7354740 0.80 DRD2 (0.40) CYP3A4USP2MAPTHTTPOLB
SCHEMBL21689951 0.79 ALDH1A1 (0.51) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL19894409 0.78 GLRA1 (0.49) SMN1; SMN2MAPTHTTNPSR1NPC1
SCHEMBL10498397 0.77 KMT2A (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3601372-B1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEM CO (US) 2024-11-06 EP disclosed
EP-3601369-B1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEM CO (US) 2024-09-18 EP disclosed
US-12006375-B2 Regioselectively substituted cellulose esters EASTMAN CHEMICAL COMPANY (US) 2024-06-11 US disclosed
EP-3601371-B1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEM CO (US) 2024-04-10 EP disclosed
US-11939407-B2 Regioselectively substituted cellulose esters EASTMAN CHEMICAL COMPANY (US) 2024-03-26 US disclosed
US-20230167201-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEMICAL COMPANY (US) 2023-06-01 US disclosed
US-20230113238-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEMICAL COMPANY (US) 2023-04-13 US disclosed
US-11591411-B2 Regioselectively substituted cellulose esters EASTMAN CHEMICAL COMPANY (US) 2023-02-28 US disclosed
US-11505622-B2 Regioselectively substituted cellulose esters EASTMAN CHEMICAL COMPANY (US) 2022-11-22 US disclosed
CN-110506061-B Regioselectively substituted cellulose esters 伊士曼化工公司 2022-10-21 CN disclosed
EP-3601370-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS Eastman Chemical Company (US) 2020-02-05 EP disclosed
EP-3601369-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS Eastman Chemical Company (US) 2020-02-05 EP disclosed
EP-3601371-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS Eastman Chemical Company (US) 2020-02-05 EP disclosed
EP-3601372-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS Eastman Chemical Company (US) 2020-02-05 EP disclosed
WO-2018183466-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEMICAL COMPANY (US) 2018-10-04 WO disclosed
WO-2018183472-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEMICAL COMPANY (US) 2018-10-04 WO disclosed
WO-2018183463-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEMICAL COMPANY (US) 2018-10-04 WO disclosed
WO-2018183467-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS EASTMAN CHEMICAL COMPANY (US) 2018-10-04 WO disclosed
US-7875631-B2 e.g.1-(3,5-dichlorophenyl)-2-formyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; to prevent and/or treat cancer and other abnormal cell growth, and metabolic as well as blood vessel proliferate disorders, in which uncontrolled expression of insulin-like growth factor-1 receptor is observed ANALYTECON S.A. (CH) 2011-01-25 US disclosed
US-5175172-A Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients DIETLIN FRANCOIS (FR) 1992-12-29 US disclosed