Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498917 | 0.88 | KDM4E (0.54) | KDM4ESMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL10502876 | 0.83 | CA1 (0.44) | KDM4ESMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL10688914 | 0.82 | HCRTR1 (0.43) | KDM4ESMN1; SMN2 | |
| SCHEMBL9741957 | 0.81 | SMN1; SMN2 (0.55) | KDM4ESMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL10867034 | 0.80 | SMN1; SMN2 (0.67) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10865204 | 0.79 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9474698 | 0.78 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1POLBHTT | |
| SCHEMBL9591445 | 0.78 | KDM4E (0.58) | KDM4ESMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL10920467 | 0.76 | KMT2A (0.42) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10866779 | 0.74 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173319-A1 | Substituted arylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |