Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513310 | 0.82 | ALDH1A1 (0.39) | PRMT5IDO1PDK2HDAC3HDAC1 | |
| SCHEMBL14958528 | 0.81 | KDM4E (0.36) | IDO1TSHRALDH1A1HTTHPGD | |
| SCHEMBL2502932 | 0.80 | IDO1 (0.35) | IDO1ALDH1A1HTTTP53 | |
| SCHEMBL16245167 | 0.76 | TSHR (0.46) | PRMT5HDAC3HDAC1TSHRALDH1A1 | |
| SCHEMBL23978134 | 0.74 | ALDH1A1 (0.39) | PRMT5IDO1PDK2HDAC3HDAC1 | |
| SCHEMBL3145722 | 0.74 | LMNA (0.46) | PRMT5HDAC3HDAC1TSHRALDH1A1 | |
| SCHEMBL534811 | 0.74 | HTT (0.56) | TSHRALDH1A1HTTHPGDTP53 | |
| SCHEMBL29083919 | 0.74 | PRMT5 (0.37) | PRMT5PDK2HDAC3HDAC1TSHR | |
| SCHEMBL31617745 | 0.74 | HTT (0.56) | TSHRALDH1A1HTTHPGDTP53 | |
| SCHEMBL13879655 | 0.74 | AKT1 (0.42) | PRMT5HDAC3HDAC1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889904-A | HEATING MIXTURE OF ALKOXY-FUNCTIONAL DISILANE AND EITHER ALKOXY-FUNCTIONAL SILANE WITH UNSATURATED SUBSTITUENT OR UNSATURATED HYDROCARBON | DOW CORNING CORPORATION (US) | 1989-12-26 | — | — | US | claimed |
| US-8871890-B2 | Curable resin composition and cured article | DAICEL CORPORATION (JP) | 2014-10-28 | — | — | US | disclosed |
| EP-2636706-A1 | CURABLE RESIN COMPOSITION AND CURED ARTICLE | Daicel Corporation (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130131265-A1 | CURABLE RESIN COMPOSITION AND CURED ARTICLE | DAICEL CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |