Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145722 | 0.80 | LMNA (0.46) | ALDH1A1LMNAPRMT5TSHRHDAC3 | |
| SCHEMBL2513310 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAPRMT5IDO1PDK2 | |
| SCHEMBL17064010 | 0.79 | PRMT5 (0.38) | ALDH1A1LMNAPRMT5PDK2TSHR | |
| SCHEMBL16245167 | 0.78 | TSHR (0.46) | ALDH1A1LMNAPRMT5TSHRHDAC3 | |
| SCHEMBL21319068 | 0.77 | GABRA1 (0.44) | ALDH1A1LMNATSHRMAPTTP53 | |
| SCHEMBL29083919 | 0.76 | PRMT5 (0.37) | ALDH1A1LMNAPRMT5PDK2TSHR | |
| SCHEMBL534811 | 0.76 | HTT (0.56) | ALDH1A1TSHRHPGDTDP1TP53 | |
| SCHEMBL31617745 | 0.76 | HTT (0.56) | ALDH1A1TSHRHPGDTDP1TP53 | |
| SCHEMBL648491 | 0.75 | IDO1 (0.44) | ALDH1A1IDO1PDK2TSHRKMT2A | |
| SCHEMBL6600262 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAPRMT5TSHRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903581-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |