SCHEMBL1049923

SCHEMBL1049923

C=CCC=CC(=O)OC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
CYP3A4 P08684 1/20 0.31
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
APP P05067 1/20 0.30
GABRR1 P24046 2/20 0.30
GABRR2 P28476 2/20 0.30
BLM P54132 2/20 0.30
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
GABRR3 A8MPY1 1/20 0.30
TSHR P16473 1/20 0.30
APEX1 P27695 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28811335 0.81 ALDH1A1 (0.42) LMNACYP3A4MAPTALDH1A1TSHR
SCHEMBL7066119 0.79
SCHEMBL13493080 0.76
SCHEMBL1082001 0.76
SCHEMBL5606321 0.76
SCHEMBL3984688 0.76
SCHEMBL27539866 0.76
SCHEMBL8166434 0.76
SCHEMBL997398 0.73 HCAR2 (0.37) MAPTHCAR2ALDH1A1
SCHEMBL7568618 0.72 HCAR2 (0.42) MAPTHCAR2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456764-B1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B V (NL) 2016-03-30 EP claimed
US-8927196-B2 Method of making an (alkyl)acryloyl polycarbonate SSENS B.V. (NL) 2015-01-06 US claimed
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2012-11-22 US claimed
EP-2456764-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME Ssens B.V. (NL) 2012-05-30 EP claimed
EP-2456764-B1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B V (NL) 2016-03-30 EP disclosed
US-8927196-B2 Method of making an (alkyl)acryloyl polycarbonate SSENS B.V. (NL) 2015-01-06 US disclosed
US-8927196-B2 Method of making an (alkyl)acryloyl polycarbonate SSENS B.V. (NL) 2015-01-06 US disclosed
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2012-11-22 US disclosed
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2012-11-22 US disclosed
CN-102712616-A A method of making a polymer preferably an (alkyl) acryloyl polycarbonate, the polymer and (alkyl)acryloyl polycarbonate obtained, and a biodevice comprising same SSENS B V 2012-10-03 CN disclosed
EP-2456764-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME Ssens B.V. (NL) 2012-05-30 EP disclosed
EP-2456764-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME Ssens B.V. (NL) 2012-05-30 EP disclosed
WO-2011009478-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2011-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME TET3, ALKBH3, ALKBH1 LMNA 3269/4885CYP3A4 268/4885ABCC4 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.