Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499520 | 0.86 | ELANE (0.49) | LMNAMAPTELANEHPGDHSD17B10 | |
| SCHEMBL10499244 | 0.84 | ELANE (0.47) | LMNAMAPTELANEHSD17B10SMN1; SMN2 | |
| SCHEMBL10499574 | 0.83 | LMNA (0.50) | LMNAMAPTELANEHPGDCYP11B1 | |
| SCHEMBL10911760 | 0.83 | LMNA (0.50) | LMNAMAPTELANEHPGDCYP11B1 | |
| SCHEMBL7799652 | 0.81 | ELANE (0.69) | LMNAMAPTELANEHPGDCYP11B1 | |
| SCHEMBL76135 | 0.81 | LMNA (0.64) | LMNAMAPTELANEHPGDCYP11B1 | |
| SCHEMBL10500433 | 0.81 | MAPT (0.49) | LMNAMAPTELANECYP11B1CYP11B2 | |
| Ammonia Solution, Strong SCHEMBL22437493 | 0.79 | LMNA (0.61) | LMNAMAPTELANEHPGDCYP11B1 | |
| SCHEMBL18184942 | 0.79 | LMNA (0.61) | LMNAMAPTELANEHPGDCYP11B1 | |
| Hydrochloric Acid SCHEMBL27466889 | 0.79 | LMNA (0.61) | LMNAMAPTELANEHPGDCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849419-A | 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-07-18 | — | — | US | disclosed |
| EP-0174561-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |