Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499301 | 0.86 | LMNA (0.55) | ELANEKMT2AHSD17B10MAPTLMNA | |
| SCHEMBL10499244 | 0.86 | ELANE (0.47) | ELANEKMT2AHSD17B10CES2CES1 | |
| SCHEMBL10499758 | 0.83 | MAPT (0.50) | KMT2ACES2CES1MAPTALDH1A1 | |
| SCHEMBL269441 | 0.83 | ALDH1A1 (0.65) | KMT2ACES2CES1MAPTALDH1A1 | |
| SCHEMBL10500154 | 0.83 | LMNA (0.46) | KMT2AHSD17B10CES2CES1MAPT | |
| SCHEMBL10500433 | 0.82 | MAPT (0.49) | ELANEKMT2AHSD17B10MAPTALDH1A1 | |
| SCHEMBL24654488 | 0.81 | CES2 (0.59) | KMT2ACES2CES1MAPTALDH1A1 | |
| SCHEMBL29763732 | 0.81 | CES2 (0.59) | KMT2ACES2CES1MAPTALDH1A1 | |
| SCHEMBL12023642 | 0.81 | LMNA (0.53) | ELANEKMT2AHSD17B10CES2CES1 | |
| SCHEMBL20712501 | 0.81 | LMNA (0.53) | ELANEKMT2AHSD17B10CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849419-A | 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-07-18 | — | — | US | disclosed |
| EP-0174561-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |