Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499439 | 0.81 | CYP3A4 (0.41) | PRSS1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL10500144 | 0.80 | AR (0.35) | PRSS1HSP90AA1HSP90AB1TNIKGAA | |
| Hydrochloric Acid SCHEMBL10499227 | 0.79 | PRSS1 (0.35) | PRSS1HSP90AA1HSP90AB1GAA | |
| SCHEMBL10499428 | 0.76 | HSD17B10 (0.50) | HSP90AA1ALDH1A1HSD17B10XDHSLC22A12 | |
| SCHEMBL10499251 | 0.75 | PRSS1 (0.52) | PRSS1HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL10499969 | 0.75 | PRSS1 (0.52) | PRSS1HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL10499489 | 0.75 | PRSS1 (0.52) | PRSS1HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| Bromide SCHEMBL10499280 | 0.74 | PRSS1 (0.50) | PRSS1HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL10499088 | 0.73 | PRSS1 (0.50) | PRSS1HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL5033272 | 0.72 | TNIK (0.40) | TNIKXDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |