Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | LIPE | Q05469 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14513363 | 0.87 | SMN1; SMN2 (0.61) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL307002 | 0.84 | CYP2C9 (0.57) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL5647172 | 0.83 | MAPK1 (1.00) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL306371 | 0.83 | CYP2C9 (0.56) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL10854830 | 0.82 | MAPK1 (0.97) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL8465511 | 0.81 | MAPK1 (0.71) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL4912414 | 0.80 | CYP2C9 (0.53) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL4909330 | 0.79 | ALDH1A1 (0.48) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL4910664 | 0.78 | LMNA (0.50) | MAPK1CYP2C9SMN1; SMN2LMNATSHR | |
| SCHEMBL9168922 | 0.78 | SMN1; SMN2 (0.47) | MAPK1CYP2C9SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305593-A2 | Intermediates for cyanamides of 2-pyridinyloxyphenoxypropionic acid | CIBA-GEIGY AG (CH) | 1989-03-08 | — | — | EP | claimed |
| EP-0148119-B1 | AMIDES OF 2-PHENOXYPROPIONIC ACID | CIBA-GEIGY AG (CH) | 1989-05-03 | — | — | EP | disclosed |
| EP-0305593-A2 | Intermediates for cyanamides of 2-pyridinyloxyphenoxypropionic acid | CIBA-GEIGY AG (CH) | 1989-03-08 | — | — | EP | disclosed |
| US-4759796-A | Used together with a carrier and other adjuvant | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| US-4640703-A | CONTROLLING GRASSES IN CROPS | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | disclosed |
| EP-0148119-A2 | Amides of 2-phenoxypropionic acid | CIBA-GEIGY AG (CH) | 1985-07-10 | — | — | EP | disclosed |