Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 4/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684051 | 0.87 | SMN1; SMN2 (0.65) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL7885684 | 0.85 | LTA4H (0.52) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL8688733 | 0.85 | L3MBTL1 (0.52) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL10499451 | 0.78 | MAPK1 (0.71) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL14513363 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL306371 | 0.77 | CYP2C9 (0.56) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL8689392 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL9168919 | 0.76 | MAP4K4 (0.54) | SMN1; SMN2TSHRLMNACYP2C9APEX1 | |
| SCHEMBL8683713 | 0.76 | LIPE (0.52) | LMNAL3MBTL1MCL1LIPEMMP2 | |
| SCHEMBL8582394 | 0.76 | L3MBTL1 (0.61) | L3MBTL1MCL1FFAR4MMP2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274100-A | Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids | CIBA-GEIGY CORPORATION (US) | 1993-12-28 | — | — | US | claimed |
| EP-0483061-A2 | Process for the preparation of 4-(3-fluoro-pyridine-2-yloxy)-phenoxy-propionic acids | CIBA-GEIGY AG (CH) | 1992-04-29 | — | — | EP | claimed |
| EP-0483061-B1 | Process for the preparation of 4-(3-fluoro-pyridine-2-yloxy)-phenoxy-propionic acids | CIBA GEIGY AG (CH) | 1995-05-17 | — | — | EP | disclosed |
| US-5274100-A | Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids | CIBA-GEIGY CORPORATION (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0483061-A2 | Process for the preparation of 4-(3-fluoro-pyridine-2-yloxy)-phenoxy-propionic acids | CIBA-GEIGY AG (CH) | 1992-04-29 | — | — | EP | disclosed |