Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756319 | 0.87 | ALDH1A1 (0.69) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7108913 | 0.82 | GAA (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10499445 | 0.81 | KMT2A (0.52) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17620596 | 0.80 | ALDH1A1 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8551297 | 0.80 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL850500 | 0.79 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10499076 | 0.79 | GAA (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10499360 | 0.79 | GAA (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10498915 | 0.79 | GAA (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL15883219 | 0.79 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |