Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 7/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892327 | 0.88 | HDAC3 (0.66) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL11892329 | 0.88 | EGFR (0.56) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL11195217 | 0.88 | KMT2A (0.56) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL10602106 | 0.82 | CNR1 (0.66) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10499564 | 0.81 | HDAC3 (0.57) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL1822139 | 0.78 | KMT2A (0.59) | KMT2AEGFRKDM4CEPHX2MEN1 | |
| SCHEMBL8548740 | 0.77 | ALDH1A1 (0.69) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2678367 | 0.76 | CNR1 (0.74) | KMT2AMEN1MAPT | |
| SCHEMBL2678363 | 0.76 | CNR1 (0.74) | KMT2AMEN1MAPT | |
| SCHEMBL23051369 | 0.76 | KMT2A (0.56) | KMT2AEGFRKDM4CEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |