Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503560 | 0.89 | S100A4 (0.55) | S100A4HKDC1MEN1MAPTKMT2A | |
| SCHEMBL10502055 | 0.81 | MAPT (0.70) | S100A4HKDC1MEN1MAPTKMT2A | |
| SCHEMBL9713728 | 0.78 | S100A4 (0.49) | S100A4BCL2MCL1PTPN1CDC25A | |
| SCHEMBL29378883 | 0.77 | S100A4 (0.87) | S100A4MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL155593 | 0.77 | S100A4 (0.87) | S100A4MEN1MAPTKMT2ANPSR1 | |
| Anthraquinone SCHEMBL10531854 | 0.77 | S100A4 (0.87) | S100A4MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL17250512 | 0.77 | IDO1 (0.56) | S100A4HKDC1MEN1MAPTKMT2A | |
| SCHEMBL11041338 | 0.75 | ADORA2A (0.57) | S100A4MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL30419890 | 0.75 | S100A4 (0.91) | S100A4MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL301388 | 0.75 | S100A4 (0.91) | S100A4MEN1MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146145-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4593120-A | Naphthalene-1,4-dicarboxylic acid group | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0146145-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-06-26 | — | — | EP | disclosed |