Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | FGB | P02675 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628987 | 0.79 | ADORA2A (0.53) | ADORA2AMEN1KMT2APOLBFGB | |
| SCHEMBL10502575 | 0.75 | S100A4 (0.59) | ADORA2AMEN1KMT2AS100A4MAPT | |
| SCHEMBL10777248 | 0.75 | S100A4 (0.52) | ADORA2AMEN1KMT2APOLBS100A4 | |
| SCHEMBL9846592 | 0.74 | ADORA2A (0.68) | ADORA2AMEN1KMT2APOLBS100A4 | |
| SCHEMBL8777815 | 0.74 | ADORA2A (0.68) | ADORA2AMEN1KMT2APOLBS100A4 | |
| SCHEMBL13944330 | 0.73 | ADORA2A (1.00) | ADORA2AMEN1KMT2APOLBFGB | |
| SCHEMBL9846490 | 0.72 | ADORA2A (0.55) | ADORA2AMEN1KMT2APOLBMAPK1 | |
| SCHEMBL9846455 | 0.72 | ADORA2A (0.55) | ADORA2AMEN1KMT2APOLBMAPK1 | |
| SCHEMBL8092263 | 0.72 | ADORA2A (0.80) | ADORA2AMEN1KMT2APOLBFGB | |
| SCHEMBL1038701 | 0.71 | ALDH1A1 (0.66) | ADORA2AMEN1KMT2APOLBFGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019285-B1 | PROCESS FOR PREPARING ASYMMETRICAL VAT DYESTUFFS OF THE ANTHRAQUINONE SERIES AND THEIR USE IN DYEING AND PRINTING | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |
| US-4329456-A | ACYLATION WITHOUT INTERMEDIATE ISOLATION | CIBA-GEIGY AG (CH) | 1982-05-11 | — | — | US | disclosed |
| EP-0019285-A1 | Process for preparing asymmetrical vat dyestuffs of the anthraquinone series and their use in dyeing and printing | CIBA-GEIGY AG (CH) | 1980-11-26 | — | — | EP | disclosed |