Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 3/20 | 0.40 |
| ▸ | CDC25A | P30304 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 3/20 | 0.40 |
| ▸ | P4HB | P07237 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17250106 | 0.82 | SOAT1 (0.61) | S100A4SOAT1MAP2K7CDC25ACDC25B | |
| SCHEMBL17250118 | 0.80 | G6PD (0.49) | S100A4SOAT1BCL2MCL1MAP2K7 | |
| SCHEMBL10502575 | 0.78 | S100A4 (0.59) | S100A4PTPN1BCL2MCL1CDC25A | |
| SCHEMBL9713833 | 0.78 | SOAT1 (0.61) | S100A4PTPN1SOAT1MAP2K7CDC25A | |
| SCHEMBL9713138 | 0.75 | MAP2K7 (0.44) | S100A4PTPN1SOAT1MAP2K7CDC25A | |
| SCHEMBL8773066 | 0.71 | S100A4 (0.56) | S100A4PTPN1HSP90AA1 | |
| SCHEMBL7919414 | 0.70 | USP2 (0.43) | S100A4PTPN1SOAT1BCL2MCL1 | |
| Diphenylsulfane SCHEMBL27631759 | 0.70 | MAOA (0.73) | S100A4 | |
| SCHEMBL9713769 | 0.70 | GAPDH (0.69) | S100A4PTPN1CDC25ACDC25BHSP90AA1 | |
| SCHEMBL15251827 | 0.69 | PTPN1 (0.55) | S100A4PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |