Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503760 | 0.97 | L3MBTL1 (0.48) | L3MBTL1SLC2A1NPSR1ALDH1A1CASR | |
| Fumaric Acid SCHEMBL10592582 | 0.95 | L3MBTL1 (0.44) | L3MBTL1SLC2A1NPSR1ALDH1A1CASR | |
| SCHEMBL10504030 | 0.92 | SLC2A1 (0.46) | L3MBTL1SLC2A1ALDH1A1CASRKMT2A | |
| SCHEMBL10504761 | 0.91 | L3MBTL1 (0.47) | L3MBTL1SLC2A1NPSR1ALDH1A1CASR | |
| SCHEMBL10504594 | 0.90 | SLC2A1 (0.47) | L3MBTL1SLC2A1ALDH1A1CASRKMT2A | |
| SCHEMBL10592577 | 0.87 | L3MBTL1 (0.35) | L3MBTL1NPSR1ALDH1A1KDM4EPTGS1 | |
| SCHEMBL10506877 | 0.85 | L3MBTL1 (0.48) | L3MBTL1SLC2A1NPSR1ALDH1A1CASR | |
| SCHEMBL10504203 | 0.83 | L3MBTL1 (0.49) | L3MBTL1SLC2A1NPSR1ALDH1A1CASR | |
| SCHEMBL10503951 | 0.83 | GRK3 (0.40) | L3MBTL1CASRKMT2AMEN1ADRB2 | |
| SCHEMBL10592973 | 0.82 | CASR (0.49) | CASRKMT2AMEN1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |