Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | GRK3 | P35626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592061 | 0.97 | CASR (0.50) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10593339 | 0.90 | ADRB2 (0.47) | CASRADRB2ADRB1LMNACYP1A2 | |
| SCHEMBL10592451 | 0.90 | ADRB2 (0.41) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10503940 | 0.89 | ADRB2 (0.41) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10503702 | 0.89 | CYP2D6 (0.49) | CASRADRB2ADRB1LMNACYP1A2 | |
| SCHEMBL10594588 | 0.88 | CYP2D6 (0.45) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10504063 | 0.88 | HTR1A (0.55) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10503951 | 0.88 | GRK3 (0.40) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10594410 | 0.88 | ADRB2 (0.42) | CASRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL10503207 | 0.87 | ADRB2 (0.39) | CASRADRB2ADRB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |