Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504594 | 0.97 | SLC2A1 (0.47) | SLC2A1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL10503152 | 0.92 | L3MBTL1 (0.48) | SLC2A1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL10503760 | 0.90 | L3MBTL1 (0.48) | SLC2A1MEN1KMT2AL3MBTL1HPGD | |
| Fumaric Acid SCHEMBL10592582 | 0.88 | L3MBTL1 (0.44) | SLC2A1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL10504638 | 0.88 | SLC2A1 (0.46) | SLC2A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10592973 | 0.83 | CASR (0.49) | MEN1KMT2ASMN1; SMN2KDM4ECASR | |
| SCHEMBL10504761 | 0.83 | L3MBTL1 (0.47) | SLC2A1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL10503951 | 0.82 | GRK3 (0.40) | MEN1KMT2AL3MBTL1CASRADRB2 | |
| SCHEMBL10507089 | 0.81 | L3MBTL1 (0.38) | L3MBTL1CASRADRB2ADRB1ADRB3 | |
| SCHEMBL10592451 | 0.81 | ADRB2 (0.41) | MEN1KMT2ACASRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |