Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456419 | 0.77 | CYP19A1 (0.52) | HPGDTSHRALDH1A1MAPTCYP1A2 | |
| SCHEMBL9634058 | 0.74 | CYP19A1 (0.42) | HPGDTSHRALDH1A1MAPTCYP1A2 | |
| SCHEMBL14254671 | 0.73 | DRD2 (0.56) | ALDH1A1MAPTCYP1A2POLBCYP3A4 | |
| SCHEMBL14254673 | 0.73 | DRD2 (0.56) | ALDH1A1MAPTCYP1A2POLBCYP3A4 | |
| SCHEMBL14540070 | 0.73 | DRD2 (0.56) | ALDH1A1MAPTCYP1A2POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL5412784 | 0.71 | HPGD (0.62) | HPGDTSHRALDH1A1MAPTDPP4 | |
| Hydrochloric Acid SCHEMBL6872103 | 0.71 | HPGD (0.62) | HPGDTSHRALDH1A1MAPTDPP4 | |
| SCHEMBL10503567 | 0.70 | HPGD (0.54) | HPGDTSHRALDH1A1MAPTDPP4 | |
| SCHEMBL11021735 | 0.69 | HPGD (0.64) | HPGDTSHRALDH1A1MAPTDPP4 | |
| SCHEMBL4925533 | 0.69 | HPGD (0.64) | HPGDTSHRALDH1A1MAPTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136658-B1 | -1-BENZYL-AMINOALKYL-PYRROLIDINONES AND THEIR ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUNDS CONTAINING THEM | BOEHRINGER INGELHEIM KG (DE) | 1989-04-26 | — | — | EP | disclosed |