Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503154 | 0.74 | HPGD (0.51) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL13484174 | 0.73 | HPGD (0.47) | MAPTBRD4HPGDTSHRGRM2 | |
| SCHEMBL9633705 | 0.73 | MC4R (0.46) | MAPTBRD4HPGDTSHRGRM2 | |
| SCHEMBL9766998 | 0.72 | HPGD (0.46) | POLBCYP2D6BRD4HPGDTSHR | |
| SCHEMBL3201676 | 0.71 | DPP4 (0.50) | BRD4HPGDTSHRGRM2PREP | |
| SCHEMBL3185962 | 0.71 | DPP4 (0.50) | BRD4HPGDTSHRGRM2PREP | |
| SCHEMBL3201687 | 0.71 | DPP4 (0.50) | BRD4HPGDTSHRGRM2PREP | |
| SCHEMBL27623771 | 0.71 | BRD4 (0.47) | BRD4HPGDTSHRGRM2PREP | |
| SCHEMBL9803156 | 0.69 | HPGD (0.43) | BRD4HPGDTSHRGRM2PREP | |
| SCHEMBL9767456 | 0.69 | HPGD (0.43) | BRD4HPGDTSHRGRM2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149808-A | Nootropics, antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5073671-A | Nootropic and antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1991-12-17 | — | — | US | disclosed |
| US-4833140-A | ANTIHYPOXIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1989-05-23 | — | — | US | disclosed |
| US-4767759-A | ANTIHYPOXICS | BOEHRINGER INGELHEIM KG (DE) | 1988-08-30 | — | — | US | disclosed |