Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867785 | 0.86 | NPC1 (0.36) | ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL10563335 | 0.85 | KDM4E (0.43) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL9684325 | 0.79 | MAPT (0.46) | ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL9480849 | 0.78 | POLB (0.34) | ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL10918288 | 0.77 | SLC22A12 (0.39) | — | |
| SCHEMBL10500864 | 0.76 | SLC22A12 (0.43) | ALDH1A1 | |
| SCHEMBL10868380 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL10761883 | 0.72 | HPGD (0.45) | ALDH1A1NPC1MAPTGAAHTT | |
| SCHEMBL11170537 | 0.72 | MAPT (0.43) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10756516 | 0.72 | FBP1 (0.39) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797484-A | REACTING GUANIDINE DERIVATIVE WITH SULPHONYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |