Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10755155 | 0.87 | MAPT (0.41) | MAPTNPC1RAB9AKAT6A | |
| SCHEMBL9480849 | 0.86 | POLB (0.34) | MAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL10500864 | 0.85 | SLC22A12 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10563335 | 0.81 | KDM4E (0.43) | MAPTNPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL10503157 | 0.79 | ALDH1A1 (0.31) | MAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL10918288 | 0.79 | SLC22A12 (0.39) | MEN1KMT2A | |
| SCHEMBL10641478 | 0.76 | ALDH1A1 (0.44) | MAPTNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9759975 | 0.76 | EDNRA (0.47) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10761883 | 0.75 | HPGD (0.45) | MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL10756516 | 0.75 | FBP1 (0.39) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | disclosed |