Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505436 | 0.98 | ADRB2 (0.40) | ADRB2ADRB1CASRADRB3MEN1 | |
| SCHEMBL10592973 | 0.87 | CASR (0.49) | ADRB2ADRB1CASRADRB3MEN1 | |
| SCHEMBL10592451 | 0.87 | ADRB2 (0.41) | ADRB2ADRB1CASRADRB3MEN1 | |
| SCHEMBL10593339 | 0.87 | ADRB2 (0.47) | ADRB2ADRB1CASRADRB3HTR1A | |
| SCHEMBL10592061 | 0.85 | CASR (0.50) | ADRB2ADRB1CASRADRB3MEN1 | |
| SCHEMBL10594410 | 0.84 | ADRB2 (0.42) | ADRB2ADRB1CASRADRB3MEN1 | |
| SCHEMBL10504326 | 0.84 | ADRB2 (0.51) | ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL10503940 | 0.83 | ADRB2 (0.41) | ADRB2ADRB1CASRADRB3MEN1 | |
| SCHEMBL10503702 | 0.83 | CYP2D6 (0.49) | ADRB2ADRB1CASRADRB3HTR1A | |
| SCHEMBL10594588 | 0.83 | CYP2D6 (0.45) | ADRB2ADRB1CASRADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |