Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504326 | 0.92 | ADRB2 (0.51) | ADRB2ADRB1HTR1ALMNACYP1A2 | |
| SCHEMBL10592973 | 0.90 | CASR (0.49) | ADRB2ADRB1LMNACYP1A2CASR | |
| SCHEMBL10503250 | 0.90 | ADRB2 (0.51) | ADRB2ADRB1HTR1ALMNACYP1A2 | |
| SCHEMBL10592451 | 0.88 | ADRB2 (0.41) | ADRB2ADRB1CASRADRB3 | |
| SCHEMBL10592061 | 0.88 | CASR (0.50) | ADRB2ADRB1LMNACYP1A2CASR | |
| SCHEMBL10503528 | 0.87 | ADRB2 (0.47) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL10503207 | 0.87 | ADRB2 (0.39) | ADRB2ADRB1HTR1ACASRADRB3 | |
| SCHEMBL10503702 | 0.86 | CYP2D6 (0.49) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL10503940 | 0.86 | ADRB2 (0.41) | ADRB2ADRB1CASRADRB3 | |
| SCHEMBL10594588 | 0.86 | CYP2D6 (0.45) | ADRB2ADRB1CYP1A2CYP2D6CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |