Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.52 |
| ▸ | MPI | P34949 | 2/20 | 0.51 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | PMM2 | O15305 | 1/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYBB | P04839 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501626 | 0.88 | METAP2 (0.59) | METAP2MPIPHOSPHO1TDP1KDM4E | |
| SCHEMBL10501435 | 0.86 | SMN1; SMN2 (0.45) | METAP2TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL10501489 | 0.81 | METAP2 (0.64) | METAP2MPIPHOSPHO1 | |
| SCHEMBL10502224 | 0.80 | MPI (0.62) | METAP2MPIPHOSPHO1TDP1KDM4E | |
| SCHEMBL10501929 | 0.78 | METAP2 (0.64) | METAP2MPIPHOSPHO1TDP1KDM4E | |
| SCHEMBL10502027 | 0.75 | METAP2 (0.62) | METAP2MPIPHOSPHO1 | |
| SCHEMBL10502317 | 0.75 | MPI (0.67) | METAP2MPIPHOSPHO1 | |
| SCHEMBL10501672 | 0.75 | MPI (0.72) | METAP2MPIPHOSPHO1TDP1KDM4E | |
| SCHEMBL10502075 | 0.75 | METAP2 (0.68) | METAP2ALDH1A1POLB | |
| SCHEMBL5916849 | 0.74 | LMNA (0.48) | METAP2MPIPHOSPHO1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |