Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584940 | 0.78 | ALDH1A1 (0.55) | LMNAALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL27808158 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTTDP1KMT2AGAA | |
| SCHEMBL134091 | 0.76 | ALDH1A1 (0.59) | LMNAALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL9561790 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTTDP1KMT2AGAA | |
| SCHEMBL10507280 | 0.74 | CRHBP (0.47) | LMNACTSVCTSLALDH1A1MAPT | |
| SCHEMBL1644599 | 0.73 | ALDH1A1 (0.58) | CTSVCTSLALDH1A1MAPTTDP1 | |
| SCHEMBL5864201 | 0.73 | ALDH1A1 (0.58) | CTSVCTSLALDH1A1MAPTTDP1 | |
| Phenyl Ethanol SCHEMBL8170091 | 0.73 | TP53 (0.53) | ALDH1A1ALOX5MAPTTDP1KMT2A | |
| SCHEMBL27245285 | 0.73 | ALDH1A1 (0.54) | LMNACTSVCTSLALDH1A1MAPT | |
| SCHEMBL29222890 | 0.72 | PTGS2 (0.55) | ALDH1A1MAPTTDP1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864031-A | Process for the resolution of D,L-racemic mixtures | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1989-09-05 | — | — | US | claimed |
| EP-0225503-B1 | RESOLUTION SYSTEM | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1989-08-02 | — | — | EP | claimed |
| EP-0225503-A1 | Resolution system | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1987-06-16 | — | — | EP | claimed |