Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504556 | 0.91 | L3MBTL1 (0.39) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10507089 | 0.84 | L3MBTL1 (0.38) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10506877 | 0.82 | L3MBTL1 (0.48) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| Fumaric Acid SCHEMBL10593162 | 0.80 | PDE5A (0.36) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10505550 | 0.80 | L3MBTL1 (0.38) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10506404 | 0.79 | CYP2D6 (0.49) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL10503105 | 0.77 | ADRB2 (0.50) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL10593421 | 0.77 | ADRB2 (0.42) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10503441 | 0.77 | ADRB2 (0.36) | L3MBTL1ACHEADRB2ADRB1ADRB3 | |
| Fumaric Acid SCHEMBL10592889 | 0.77 | L3MBTL1 (0.35) | L3MBTL1ACHEADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |