Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503636 | 1.00 | ADRB2 (0.34) | ADRB2ADRB1ABCB1KDM4EUSP2 | |
| Fumaric Acid SCHEMBL10594610 | 0.95 | ADRB2 (0.34) | ADRB2ADRB1ABCB1LMNAMAPT | |
| SCHEMBL10594601 | 0.88 | ADRB2 (0.41) | ADRB2ADRB1USP2MAPTADRB3 | |
| SCHEMBL10594603 | 0.88 | KDM4E (0.31) | KDM4EUSP2ALDH1A1LMNAGAA | |
| SCHEMBL10505406 | 0.78 | CYP3A4 (0.35) | ADRB2ADRB1ABCB1ADRB3 | |
| SCHEMBL10593421 | 0.77 | ADRB2 (0.42) | ADRB2ADRB1USP2MAPTADRB3 | |
| SCHEMBL10505274 | 0.77 | TTPA (0.35) | ADRB2ADRB1ABCB1KDM4EALDH1A1 | |
| SCHEMBL10504278 | 0.77 | ADRB2 (0.37) | ADRB2ADRB1ABCB1 | |
| SCHEMBL10505259 | 0.74 | ADRB1 (0.36) | ADRB2ADRB1KDM4EADRB3 | |
| SCHEMBL10504605 | 0.73 | ADRB3 (0.53) | ADRB2ADRB1ABCB1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |