Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509439 | 0.84 | ADORA2B (0.50) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL9726323 | 0.84 | ADORA2B (0.50) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL9726271 | 0.82 | ALDH1A1 (0.64) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL10507556 | 0.82 | ADORA2B (0.48) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL9726284 | 0.81 | KDM4E (0.62) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL9726279 | 0.81 | ADORA2B (0.47) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL10507774 | 0.79 | ADORA2B (0.46) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL9188539 | 0.79 | ADORA2B (0.46) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL10509646 | 0.79 | ALDH1A1 (0.53) | ADORA2BALDH1A1HTTLMNAGAA | |
| SCHEMBL10550132 | 0.78 | LMNA (0.51) | ADORA2BALDH1A1HTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135491-B1 | HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS | MONSANTO COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0135491-A1 | Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters | MONSANTO COMPANY (US) | 1985-03-27 | — | — | EP | disclosed |