Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 13/20 | 0.41 |
| ▸ | CA2 | P00918 | 13/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507936 | 0.93 | KMT2A (0.48) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL10507989 | 0.92 | MEN1 (0.49) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL6507932 | 0.84 | ATM (0.52) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL14546320 | 0.83 | ATM (0.49) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL10505597 | 0.83 | PYGL (0.48) | MEN1KMT2AUSP2MAPTALOX15 | |
| SCHEMBL10505642 | 0.83 | MEN1 (0.47) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL350841 | 0.81 | KMT2A (0.58) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL10506547 | 0.78 | MEN1 (0.45) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL4150636 | 0.78 | KMT2A (0.36) | ATMMEN1KMT2AUSP2MAPT | |
| SCHEMBL14546321 | 0.77 | KMT2A (0.49) | ATMMEN1KMT2AUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843100-A | Benzoylureas, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0154507-A2 | Benzoylureas, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-09-11 | — | — | EP | disclosed |