SCHEMBL6507932

SCHEMBL6507932

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(S(=O)(=O)C(F)F)cc1F

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
USP2 O75604 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
CA1 P00915 10/20 0.44
CA2 P00918 10/20 0.44
CA9 Q16790 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 1/20 0.41
CA12 O43570 2/20 0.40
PPIA P62937 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14546320 0.85 ATM (0.49) ATMMEN1KMT2AUSP2MAPT
SCHEMBL10508151 0.84 ATM (0.48) ATMMEN1KMT2AUSP2MAPT
SCHEMBL10507989 0.83 MEN1 (0.49) ATMMEN1KMT2AUSP2MAPT
SCHEMBL5311223 0.80 ATM (0.56) ATMMEN1KMT2AUSP2MAPT
SCHEMBL8657856 0.79 KMT2A (0.59) ATMMEN1KMT2AMAPTHTT
SCHEMBL14546321 0.78 KMT2A (0.49) ATMMEN1KMT2AUSP2MAPT
SCHEMBL6509510 0.78 ATM (0.52) ATMMEN1KMT2AUSP2MAPT
SCHEMBL10507936 0.77 KMT2A (0.48) ATMMEN1KMT2AUSP2MAPT
SCHEMBL8658188 0.77 MEN1 (0.56) ATMMEN1KMT2AUSP2MAPT
SCHEMBL8660904 0.77 KMT2A (0.64) ATMMEN1KMT2AUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 ATM 2564/4885MEN1 2593/4885KMT2A 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.