Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546320 | 0.93 | ATM (0.49) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL10507936 | 0.85 | KMT2A (0.48) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL5316465 | 0.79 | KMT2A (0.55) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL6507932 | 0.78 | ATM (0.52) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL13235108 | 0.78 | KMT2A (0.50) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL10507156 | 0.78 | KMT2A (0.48) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL10507989 | 0.78 | MEN1 (0.49) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL6505618 | 0.77 | KMT2A (0.50) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL6511477 | 0.77 | KMT2A (0.52) | KMT2AMAPTMEN1USP2ALOX15 | |
| SCHEMBL10508151 | 0.77 | ATM (0.48) | KMT2AMAPTMEN1USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |