Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 3/20 | 0.54 |
| ▸ | TACR3 | P29371 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218255 | 0.83 | TSHR (0.54) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL10680642 | 0.83 | TSHR (0.52) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL12768139 | 0.82 | ACHE (0.56) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL18910858 | 0.79 | ACHE (0.56) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL10678524 | 0.77 | TSHR (0.54) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL22914905 | 0.76 | DHODH (0.58) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL13338300 | 0.76 | KDM4E (0.69) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL10675207 | 0.75 | LMNA (0.60) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL10671971 | 0.75 | CYP2C9 (0.59) | TSHRLMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL7221673 | 0.75 | ADORA2A (0.60) | LMNASMN1; SMN2KDM4EPDE10ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210084-B1 | AMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-02-08 | — | — | EP | disclosed |
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| EP-0210084-A1 | Amides, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1987-01-28 | — | — | EP | disclosed |