Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | PRNP | P04156 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 3/20 | 0.50 |
| ▸ | TACR3 | P29371 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678460 | 0.84 | CYP2C9 (0.54) | CYP2C9TSHRPRNPKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10676149 | 0.83 | CYP2C9 (0.53) | CYP2C9TSHRPRNPKDM4ESMN1; SMN2 | |
| SCHEMBL10508236 | 0.75 | TSHR (0.57) | CYP2C9TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL10673820 | 0.74 | CYP2C9 (1.00) | CYP2C9TSHRRXFP1PRNPMEN1 | |
| SCHEMBL10678524 | 0.73 | TSHR (0.54) | CYP2C9TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13338300 | 0.72 | KDM4E (0.69) | TSHRMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10672389 | 0.72 | CYP2C9 (0.75) | CYP2C9TSHRRXFP1PRNPMEN1 | |
| SCHEMBL10675207 | 0.72 | LMNA (0.60) | CYP2C9TSHRKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29859762 | 0.72 | TSHR (1.00) | TSHRKDM4ESMN1; SMN2LMNAPDE10A | |
| Hydrochloric Acid SCHEMBL10674770 | 0.71 | CYP2C9 (0.57) | CYP2C9TSHRKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |