Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073604 | 0.79 | L3MBTL1 (0.52) | ALDH1A1L3MBTL1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL10508336 | 0.76 | CA1 (0.46) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL10693785 | 0.75 | GSTO1 (0.41) | MAPTKMT2AALPLMEN1 | |
| SCHEMBL19417683 | 0.73 | PTK2 (0.36) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8602441 | 0.71 | L3MBTL1 (0.60) | TSHRALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL10685495 | 0.69 | MEN1 (0.35) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11093773 | 0.68 | NPSR1 (0.35) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11084112 | 0.67 | GAA (0.35) | TSHRALDH1A1MAPTGAA | |
| SCHEMBL10947019 | 0.67 | KEAP1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7934335 | 0.66 | F2 (0.40) | KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001514-B1 | HERBICIDAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-08 | — | — | EP | disclosed |
| US-4443244-A | TRIAZINES AND PYRIMIDINES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| US-4339266-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4257802-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0001514-A2 | Herbicidal sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | disclosed |