Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692061 | 0.82 | MTNR1A (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8539852 | 0.81 | MTNR1A (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6021805 | 0.79 | MTNR1A (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL11616932 | 0.78 | CA12 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31260836 | 0.78 | HTT (0.40) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6248477 | 0.77 | MTNR1A (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7455045 | 0.77 | HTT (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29025787 | 0.77 | PTGS2 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8039889 | 0.77 | PTGS2 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL18474249 | 0.76 | CA12 (0.48) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796383-B | 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method | 湘潭大学 | 2020-09-18 | — | — | CN | claimed |
| CN-109796383-B | 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method | 湘潭大学 | 2020-09-18 | — | — | CN | disclosed |
| EP-0169581-B1 | ANTITUSSIVE AND MUCUS REGULATING 2-SUBSTITUTED THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1989-12-06 | — | — | EP | disclosed |
| US-4857643-A | Antitussive and mucus regulating 2-substituted thiazolidines | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-08-15 | — | — | US | disclosed |
| US-4798898-A | BRONCHODILATORS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-01-17 | — | — | US | disclosed |
| EP-0169581-A2 | Antitussive and mucus regulating 2-substituted thiazolidines | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1986-01-29 | — | — | EP | disclosed |