Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509697 | 0.81 | CA1 (0.53) | MTNR1AMTNR1BPOLBCTSDNPC1 | |
| SCHEMBL11692061 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BPOLBCTSDNPC1 | |
| SCHEMBL6021805 | 0.76 | MTNR1A (0.45) | MTNR1AMTNR1BPOLBCTSDNPC1 | |
| SCHEMBL11758771 | 0.75 | MTNR1A (0.51) | MTNR1AMTNR1BPOLBNPC1MEN1 | |
| SCHEMBL8536457 | 0.75 | MAPT (0.42) | NPC1RAB9ATSHRSMN1; SMN2MAPT | |
| SCHEMBL30529998 | 0.74 | KMT2A (0.44) | MTNR1AMTNR1BPOLBMEN1KMT2A | |
| SCHEMBL7455045 | 0.74 | HTT (0.44) | MTNR1AMTNR1BPOLBCTSDNPC1 | |
| SCHEMBL12470556 | 0.74 | MTNR1A (0.61) | MTNR1AMTNR1BPOLBMEN1RAB9A | |
| SCHEMBL8538646 | 0.73 | ACHE (0.50) | POLBNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL806075 | 0.73 | MTNR1A (0.60) | MTNR1AMTNR1BPOLBHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |