Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305109 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL28567773 | 0.77 | RECQL (0.64) | ALDH1A1MAPK1ALOX15HSD17B10SNCA | |
| SCHEMBL1278365 | 0.76 | SNCA (0.67) | ALDH1A1CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL17138368 | 0.76 | SNCA (0.67) | ALDH1A1CYP3A4MAPK1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL28562483 | 0.75 | RECQL (0.65) | ALDH1A1MAPK1ALOX15HSD17B10SNCA | |
| SCHEMBL8767757 | 0.75 | ALDH1A1 (0.63) | ALDH1A1CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL5149992 | 0.75 | MAPK1 (0.52) | ALDH1A1CYP3A4MAPK1L3MBTL1TSHR | |
| SCHEMBL305309 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL6482217 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL14965715 | 0.74 | TAAR1 (0.54) | ALDH1A1L3MBTL1TDP1MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163948-B1 | PROCESS FOR PRODUCING AN INDOLINE | IHARA CHEMICAL IND CO | 1989-08-16 | — | — | EP | disclosed |
| US-4673749-A | CYCLIZATION OF 2-HOLOGENO PHENETHYLAMINES WITH COPPER CATALYS T AND ALKALI DEHYROHALOGENATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-06-16 | — | — | US | disclosed |
| EP-0163948-A1 | Process for producing an indoline | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4280958-A | COPPER-TYPE CATALYST USED IN CYCLIZATION OF A HALOGENOPHENETHYLAMINE IN THE PRESENCE OF AN AMINE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4159271-A | CYCLIZATION OF A 2-HALOGENOPHENETHYLAMINE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1979-06-26 | — | — | US | disclosed |