SCHEMBL28567773

SCHEMBL28567773

NCCc1cc(O)c(O)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 4/20 0.64
TDP1 Q9NUW8 4/20 0.64
MEN1 O00255 2/20 0.64
RAD52 P43351 2/20 0.64
KMT2A Q03164 2/20 0.64
APEX1 P27695 2/20 0.64
BLM P54132 2/20 0.64
GAPDH P04406 1/20 0.64
THRB P10828 1/20 0.64
ALOX15 P16050 3/20 0.61
KDM4E B2RXH2 3/20 0.61
MAPT P10636 3/20 0.61
MAPK1 P28482 3/20 0.61
HSD17B10 Q99714 2/20 0.61
AGO2 Q9UKV8 1/20 0.61
ALOX12 P18054 1/20 0.50
TAAR1 Q96RJ0 5/20 0.45
ADRA2A P08913 2/20 0.43
DRD2 P14416 2/20 0.43
DRD1 P21728 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28562483 0.98 RECQL (0.65) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL10509984 0.79 TAAR1 (0.62) MEN1KMT2AAPEX1MAPK1TAAR1
Oxidopamine SCHEMBL37507 0.78 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL28155282 0.78 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL29367988 0.78 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
SCHEMBL10510219 0.77 ALDH1A1 (0.46) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL718426 0.76 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL30862335 0.76 RECQL (1.00) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL738049 0.76 RECQL (0.95) RECQLTDP1MEN1RAD52KMT2A
Oxidopamine SCHEMBL29419900 0.76 RECQL (0.95) RECQLTDP1MEN1RAD52KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107137338-B Hair dyeing method based on surface coating principle 苏州蓬拓生物医学科技有限公司 2021-04-06 CN claimed
CN-107137338-B Hair dyeing method based on surface coating principle 苏州蓬拓生物医学科技有限公司 2021-04-06 CN disclosed