Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitroaniline SCHEMBL29058965 | 0.86 | ALDH1A1 (0.58) | SLC1A3SLC1A2SLC1A1L3MBTL1SLC7A5 | |
| P-Nitrophenol SCHEMBL4805916 | 0.86 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5MMP1 | |
| Nitrobenzene SCHEMBL9768008 | 0.85 | ALDH1A1 (0.55) | SLC1A3SLC1A2SLC1A1L3MBTL1SLC7A5 | |
| Paranitrobenzyl Alcohol SCHEMBL5724094 | 0.81 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1SLC7A5MMP1 | |
| SCHEMBL22303821 | 0.78 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1L3MBTL1MMP1 | |
| SCHEMBL22303091 | 0.78 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1L3MBTL1MMP1 | |
| SCHEMBL22339025 | 0.78 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1L3MBTL1MMP1 | |
| SCHEMBL1913843 | 0.78 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1L3MBTL1MMP1 | |
| Methyl Alcohol SCHEMBL28785209 | 0.77 | HSPB1 (0.67) | L3MBTL1HSPB1MAOAMAOBPOLB | |
| Hydrochloric Acid SCHEMBL16868767 | 0.76 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1L3MBTL1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851526-A | ANTIARRYTHMIA, HYPOTENSIVE, ANTIISCHEMIC | SCHERING A.G. (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0306440-A2 | 1-(4-substituted phenyl)-1H-imidazoles as cardiovascular agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |