Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507649 | 1.00 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28938204 | 0.77 | RECQL (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15674249 | 0.75 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15674247 | 0.75 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28061576 | 0.74 | SCN5A (0.39) | ALDH1A1 | |
| SCHEMBL29703258 | 0.68 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4238032 | 0.68 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4772183 | 0.68 | ABL1 (0.51) | ALDH1A1KDM4EMEN1KMT2ASRC | |
| SCHEMBL4772189 | 0.68 | ABL1 (0.51) | ALDH1A1KDM4EMEN1KMT2ASRC | |
| SCHEMBL5166784 | 0.67 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164593-B1 | ANTI-INFLAMMATORY PHTHALAZINONES | FISONS CORPORATION (US) | 1989-11-15 | — | — | EP | claimed |
| EP-0164593-A1 | Anti-inflammatory phthalazinones | FISONS CORPORATION (US) | 1985-12-18 | — | — | EP | claimed |