Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512094 | 0.91 | NLRP3 (0.44) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL10510875 | 0.88 | NLRP3 (0.47) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL10510561 | 0.84 | HRAS (0.44) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL1739891 | 0.80 | POLG (0.48) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL14580321 | 0.80 | LMNA (0.55) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL1980249 | 0.80 | LMNA (0.55) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL5821 | 0.80 | LMNA (0.55) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL7154210 | 0.80 | LMNA (0.55) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL31662024 | 0.78 | LMNA (0.47) | DUTLMNATHRBMTORMDM2 | |
| SCHEMBL9801816 | 0.77 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311100-A2 | Derivatives of dideoxycytidine, their preparation and pharmaceutical use | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | claimed |
| EP-0311100-A2 | Derivatives of dideoxycytidine, their preparation and pharmaceutical use | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | disclosed |